Omar Al-Janabi

Office Address

Department of Neurology
University of Kentucky Medical Center
KY Clinic, J-401
Lexington, KY 40536-0284                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           

Personal Statement: 

Dr. Omar Al-Janabi was born in Baghdad, Iraq. He earned his medical degree from Tikrit University College of Medicine in 2009. After that, he pursued residency training in the department of neurology at Tikrit Teaching Hospital before moving to the US to earn his Masters in medical sciences and a PhD in Clinical and Translational Science both from the University of Kentucky.
Outside of his work, he enjoys spending time with his wonderful family, playing soccer, cooking Iraqi and Mediterranean foods, reading, exploring beautiful American culture, natural parks and big cities.

Graduate Studies:

2003-2009 Bachelor of Medicine, Bachelor of Surgery (M.B.Ch. B), College of Medicine, University of Tikrit, Tikrit, Salah Addin, Iraq.

2014 – 2016 Master of Science (with a major in Medical Sciences; M.S), College of Medicine, University of Kentucky, Lexington, KY.

2016 – 2019 PhD in Clinical and Translational Science, College of Medicine, University of Kentucky, Lexington, KY.

Fellowship Plans: 

Behavioral and vascular neurology

Clinical and Research Interest: 

His clinical and research interest includes developing imaging biomarkers to reliably detect subcortical white matter injury resulted from vascular disease, Alzheimer’s disease or both. As a physician-scientist, he believes in the importance of improving patient experience not only at a one-to-one patient level, but also at the population level through conducting clinical research.

Certifications:

· Advanced Cardiovascular Life Support (ACLS)

· CITI Human Subject Research Certification

· UK Neurology Handover Certification

· NIH Stroke Scale Certification

Hospital Privileges: 

University of Kentucky Chandler Medical Center

Professional Memberships: 

American Academy of Neurology

American Medical Association

Alzheimer’s Association (ISTAART) member.

Omicron Delta Kappa

Publications and Abstracts Presentations: 

Publications and Abstracts:

Nelson, P. T., Trojanowski, J. Q., Abner, E. L., Al-Janabi, O. M., Jicha, G. A., Schmitt, F. A., . . . Ighodaro, E. T. (2016). “New Old Pathologies”: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS). Journal of Neuropathology & Experimental Neurology, 75 (6), 482-498. doi: 10.1093/jnen/nlw033

Al-Janabi, O. M., Panuganti, P., Abner, E. L., et al. Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal atrophy, and White Matter Hyperintensities. Journal of Neuroimaging. doi: 10.1111/jon12494 https://www.ncbi.nlm.nih.gov/pubmed/29314393.

Al-Janabi, O. M., Brown, C. A., Bahrani, A. A., et al. Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β1 - 42 and Hypertension. Journal of Alzheimer’s Disease. Doi 10.3233/JAD-180663. https://content.iospress.com/articles/journal-of-alzheimers-disease/jad180663

Bahrani, A. A., Al-Janabi, O. M., Abner, E. L., Bardach, S. H., Kryscio, R. J., Wilcock, D. M., ... & Jicha, G. A. (2019). Post-acquisition processing confounds in brain volumetric quantification of white matter hyperintensities. Journal of neuroscience methods327, 108391.

Al-Janabi, O. M., Bauer, C. E., Goldstein, L. B., Murphy, R. R., Bahrani, A. A., Smith, C. D., ... & Jicha, G. A. (2019). White Matter Hyperintensity Regression: Comparison of Brain Atrophy and Cognitive Profiles with Progression and Stable Groups. Brain sciences9(7).

Abstracts:

Omar M. Al-Janabi, Ahmed Bahrani, Erin Abner, Charles Smith, Peter Nelson, Debra Moser, Gregory Jicha. (2016 October). Cerebrovascular Disease Risk Factors, Arteriolar Sclerosis, and Cognitive Decline in the Kentucky Appalachian “Stroke-Belt”. Poster confirmation number M208, presented at the American Neurological Association’s (ANA) 2016 Annual Meeting. http://onlinelibrary.wiley.com.ezproxy.uky.edu/doi/10.1002/ana.24759/epdf.

Omar M. Al-Janabi, Ahmed Bahrani, Erin Abner, Pradeep Panuganti, Ronan Murphy, Shani Bardach, Allison Caban-Holt, Gregory Jicha. (2017 July). Cerebrovascular Disease and Alzheimer’s Disease, but Not Aging, Are Associated with Moderate to Severe Global Cerebral Atrophy Seen on Clinical Brain Imaging Studies. Oral presentation #18115 at the Alzheimer’s Association International Conference (AAIC). AAIC. London, England. http://www.alzheimersanddementia.com/article/S1552-5260(17)33005-4/abstract

Gregory A. Jicha, Omar M. Al-Janabi, Ahmed Bahrani, Erin Abner, Ronan Murphy, Shani Bardach, Allison Caban-Holt. (2017 July). Clinical imaging, Cognitive, and Genetic Risk Profiles in Incident MCI for the Prediction of Long Term Neuropathological Outcomes at Autopsy. Poster presentation #18130 at the Alzheimer’s Association International Conference (AAIC). AAIC. London, England. http://www.alzheimersanddementia.com/article/S1552-5260(17)32245-8/abstract.

 Omar M. Al-Janabi, Christopher A. Brown, Ahmed A. Bahrani, Ronan Murphy, Charles D. Smith and Gregory A. Jicha. (September 2017). Cerebrovascular and Alzheimer’s Disease Are Associated with Different Subcortical White Matter Microstructural Damage Mechanisms. Poster number H1, presented at Poster session at the 2017 Clinical and Translational Neuroscience Exposition, Lexington, KY.    

Omar M. Al-Janabi, Christopher A. Brown, Ahmed A. Bahrani, Charles D. Smith and Gregory A. Jicha. (October 2017). Cerebrovascular and Alzheimer’s contribute to subcortical ischemic injury via independent rather than synergistic mechanisms. Poster number S170, presented at the American Neurological Association’s (ANA) 2017 Annual Meeting. San Diego, CA. http://onlinelibrary.wiley.com/doi/10.1002/ana.25024/epdf

Omar M. Al-Janabi, Christopher A. Brown, Ahmed A. Bahrani, Ronan R. Murphy, Donna Wilcock, Brian T. Gold, Larry B. Goldstein, Charles D. Smith and Gregory A. Jicha. (November 2017). Amyloid pathology and hypertension are associated with white matter injury through different mechanisms as assessed by FLAIR and DTI MRI. Poster number 26, presented at the Markesbery symposium on aging and dementia. Lexington, KY.

Ahmed A. Bahrani, Omar M. Al-Janabi, Donna Wilcock, Charles D. Smith and Gregory A. Jicha. (November 2017). MRI volumetric quantification method: sources of variability. Poster number 35, presented at the Markesbery symposium on aging and dementia. Lexington, KY.

Omar M. Al-Janabi, Christopher A. Brown, and Gregory A. Jicha. (December 2017). Distinct spatial distribution of white matter hyperintensities associated with Alzheimer’s disease pathology and hypertension. Department of Neurology’s Trainee Research Day. Lexington, KY.

Omar M. Al-Janabi and Gregory A. Jicha. (December 2017). Visual rating of dementia associated features assessed by computed tomography vs. magnetic resonance imaging, is there a difference? Department of Neurology’s Trainee Research Day. Lexington, KY.

 

Omar M. Al-Janabi, Christopher A. Brown, Ahmed A. Bahrani, Ronan R. Murphy, Donna Wilcock, Brian T. Gold, Peter T. Nelson, Larry B. Goldstein, Charles D. Smith and Gregory A. Jicha. Amyloid and hypertension are independently associated with white matter injury assessed by FLAIR and DTI MRI (poster number 174). Presented at the American Academy of Neurology 70th Annual Meeting. Los Angeles, CA. http://n.neurology.org/content/90/15_Supplement/P3.174

Omar M. Al-Janabi, Christopher A. Brown, Ahmed A. Bahrani, Ronan R. Murphy, Donna Wilcock, Brian T. Gold, Peter T. Nelson, Larry B. Goldstein, Charles D. Smith and Gregory A. Jicha. Distinct spatial distribution of white matter hyperintensities associated with Alzheimer’s disease pathology and hypertension (poster number 180). Presented at the American Academy of Neurology 70th Annual Meeting. Los Angeles, CA. http://n.neurology.org/content/90/15_Supplement/P3.180

Omar M. Al-Janabi, Ahmed A. Bahrani, Ronan R. Murphy, Peter T. Nelson, Charles D. Smith, Donna Wilcock and Gregory A. Jicha. Parietal Lobe Cerebral Microbleeds Are Associated with Lower Cerebrospinal Fluid Beta Amyloid 1-42 in Patients with Sporadic AD (poster number 40). Presented at the 13th annual CCTS conference, Lexington, KY.

Ahmed A. Bahrani, Omar M. Al-Janabi, Guoqiang Yu, Donna Wilcock, Charles D. Smith and Gregory A. Jicha. Cerebral microhemorrhage volumetric method using susceptibility weighted imaging (poster number 284). Presented at the 13th annual CCTS conference, Lexington, KY.

Omar M. Al-Janabi, Christ Brown, Richard Murphy, Brian Gold, Larry Goldstein, Charles Smith, Donna Wilcock, Gregory Jicha. (March 2018). White Matter Alterations   Due to   Alzheimer’s Disease and Hypertension Are Spatially Distinct. 10th Annual        Postdoc Poster Session. Lexington, KY.

Omar M. Al-Janabi, Ahmed A. Bahrani, Ronan R. Murphy, Peter T. Nelson, Charles D. Smith, Donna Wilcock and Gregory A. Jicha. Parietal Lobe Cerebral Microbleeds Are Associated with Lower Cerebrospinal Fluid Beta Amyloid 1-42 in Patients with Sporadic AD. Presented at the Alzheimer’s Association International Conference (AAIC) (poster number 25512). Chicago, Illinois.

Omar M. Al-Janabi, Pradeep Panuganti, Ronan R. Murphy, Peter T. Nelson, Charles D. Smith, Donna Wilcock and Gregory A. Jicha. Moderate-Severe Left Medial Temporal Lobe Atrophy Is Associated with Worse Cognitive Testing Scores in a Community Based Elderly Cohort. Presented at the Alzheimer’s Association International Conference (AAIC) (poster number 25479). Chicago, Illinois.

Omar M. Al-Janabi, Ahmed A. Bahrani, Donna Wilcock, Charles D. Smith and Gregory A. Jicha. Eliminating the Sources of Variability in a Semi-Automated WMH Quantification Method. Presented at the Alzheimer’s Imaging Conference (AIC) Preconference (poster number 25472). Chicago, Illinois.

Ahmed A. Bahrani, Omar M. Al-Janabi, Donna Wilcock, Charles D. Smith, and Gregory A. Jicha. WMH Longitudinal Study Analysis Using Different Protocols. Presented (poster number 25536) at the Alzheimer’s Imaging Conference (AIC) Preconference. Chicago, Illinois.

Omar M. Al-Janabi, Ahmed A. Bahrani, Peter T. Nelson, Charles D. Smith Donna Wilcock and Gregory A. Jicha. Exploring the Validity of Disease-Specific Masks as a Novel Non-Invasive Imaging Biomarker for Alzheimer's or Vascular Associated White Matter Hyperintensities. Presented (poster number 27) at the Appalachian Translational Research Network. Lexington, KY.

 

Omar M. Al-Janabi, Christopher E. Bauer, Larry B Goldstein, Richard R Murphy, Ahmed   A. Bahrani, Charles D. Smith, Donna M. Wilcock, Brian T Gold and Gregory A. Jicha.      White Matter Hyperintensity Regression is Associated with Better Executive Function. Presented at the 3rd Annual Kentucky Neuroscience Institute Clinical-Translational Research Symposium. Lexington, KY.

Ahmed A. Bahrani, Omar M. Al-Janabi, Donna Wilcock, Charles D. Smith, and Gregory A. Jicha. Semi-Automated Volumetric Quantifying Method of Cerebral         Microhemorrhage Using T2-Weighted MRI Images. Presented (poster number M165) at American Neurological Association’s (ANA) 2018 Annual Meeting. Atlanta, GA.

Omar M. Al-Janabi, Ahmed A. Bahrani, Peter T. Nelson, Charles D. Smith, Donna Wilcock and Gregory A. Jicha. Exploring the Validity of Disease-Specific Masks as a Novel Non-Invasive Imaging Biomarker for Alzheimer’s or Vascular Associated White Matter Hyperintensities. Presented (poster number 2018-LB-810-ANA) at American Neurological Association’s (ANA) 2018 Annual Meeting. Atlanta, GA.

Omar M. Al-Janabi, Christopher E. Bauer, Larry B Goldstein, Richard R Murphy, Ahmed A. Bahrani, Charles D. Smith, Donna M. Wilcock, Brian T Gold, and Gregory A. Jicha.     White Matter Hyperintensities Regression Association with Less Brain Atrophy Measures in ADNI2. Department of Neurology’s Trainee Research Day 2018. Lexington, KY.

Omar M. Al-Janabi, Christopher E. Bauer, Chintan Rupareliya, Larry B Goldstein,                 Richard R Murphy, Ahmed A. Bahrani, Charles D. Smith, Donna M. Wilcock, Brian T Gold, and Gregory A. Jicha. WMH Progression but not Regression is Associated with a Higher CSF tau/Aβ and Temporal Amyloid Concentration in The Amyloid PET Scan. Department of Neurology’s Trainee Research Day 2018. Lexington, KY.

Tiffany L. Sudduth, Qiang Cheng, Erin L. Abner, Richard J. Kryscio, Peter T Nelson, Brian T. Gold, Zachary Winder, Sonya Anderson, Omar M. Al-Janabi, Ahmed A. Bahrani, Gregory A Jicha, Donna M Wilcock. Identifying Predictive Fluid biomarkers for Vascular Cognitive Impairment and Dementia (VCID). The 14th International Conference on Alzheimer’s & Parkinson’s Diseases 2019. Lisbon, Portugal.

Tiffany L. Sudduth, Erin Abner, Richard Kryscio, Shawn Cheng, Larry B. Goldstein, Frederick Schmitt, Omar M. Al-Janabi, Ahmed Bahrani, Peter Nelson, Charles Smith, Brian Gold, Gregory Jicha, Donna M. Wilcock. Assessment of                 plasma and CSF for angiogenic and inflammatory proteins in a clinical cohort of patients with vascular cognitive impairment and dementia reveal potential biomarkers of disease severity. The Alzheimer’s Association International Conference (AAIC) 2019. Los Angeles, CA.

Tiffany Sudduth, Omar M. Al-Janabi, Ahmed A. Bahrani, Charles D. Smith, Qiang Cheng, Brian T. Gold, Gregory A. Jicha, Donna Wilcock. Identifying novel fluid and imaging biomarkers for small-vessel disease-mediated vascular cognitive impairment and dementia (VCID). Neuroscience 2018. San Diego, CA.

Christopher A. Brown, Omar M. Al-Janabi, Ahmed A. Bahrani, Nathan F.                 Johnson, David K. Powell, Charles D. Smith, Gregory A. Jicha, Brian T. Gold. Network-Dependent Effects of Alzheimer’s Pathology and Cerebrovascular Risk on White Matter Decline. 14th Annual CCTS Spring Conference. Lexington, KY.

Omar M. Al-Janabi, Christopher E. Bauer, Larry B Goldstein, Richard R Murphy, Ahmed A. Bahrani, Charles D. Smith, Donna M. Wilcock, Brian T Gold and Gregory A. Jicha. White Matter Hyperintensities Regression Association with Decreased Brain Atrophy & Improvement in Memory Performance. 14th Annual                 CCTS Spring Conference. Lexington, KY.

Omar M. Al-Janabi, Christopher Bauer, Chintan Rupareliya, Ahmed Bahrani, Larry Goldstein, Richard Murphy, Charles Smith, Donna Wilcock, Gregory Jicha & Brian Gold. WMH Progression but not Regression is Associated with a Higher CSF tau/Aβ and Temporal Amyloid Concentration in The Amyloid PET Scan. Presented at the American Academy of Neurology (AAN) 2019 Annual Meeting. Philadelphia. PA.  https://n.neurology.org/content/92/15_Supplement/P5.1-031.abstract

Omar M. Al-Janabi, Justin Barber, Bailee Boggess, Kevin O’Connor, Zabeen Mahuwala, Timothy Ainger, Allison Caban-Holt, Gregory Jicha & Richard Murphy. Burnout Rate Among Iraqi Neurology Residents. Presented at the American Academy of Neurology (AAN) 2019 Annual Meeting. Philadelphia. PA. https://n.neurology.org/content/92/15_Supplement/P2.9-019.abstract

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